Bnoon Fertility Services
Ovarian Rejuvenation
Exploring options for ovarian function
Ovarian rejuvenation is an emerging, investigational approach that aims to explore whether ovarian function can be supported in selected patients with reduced ovarian reserve or early ovarian insufficiency. Because evidence is still developing, ovarian rejuvenation is not a standard fertility treatment and outcomes vary significantly between individuals. At Bnoon, any ovarian rejuvenation offering should be positioned under strict clinical governance, clear eligibility criteria, and transparent counseling on what is known, what is not known, and the alternatives that are already evidence-based.
Who may inquire about ovarian rejuvenation
Ovarian rejuvenation may be discussed for patients who:
- Have diminished ovarian reserve or a low response to stimulation
- Have premature ovarian insufficiency (POI) and are exploring all options
- Are considering fertility preservation and want a full review of available pathways
- Have had repeated IVF cycles with limited follicle or egg yield
Important note: suitability requires a full fertility evaluation. In many cases, proven options — such as individualized stimulation protocols, fertility preservation, or donor pathways where applicable — may be more appropriate.
What ovarian rejuvenation may involve
- Intra-ovarian platelet-rich plasma (PRP), which is investigational
- Other experimental regenerative approaches, usually discussed in research settings
Bnoon states clearly that the exact approach, if offered, is performed only after medical review, with informed consent and a discussion of the level of evidence.
What to expect
- AMH, ultrasound for antral follicle count, and a baseline hormone profile
- Review of prior IVF cycles, if applicable, and response history
- A discussion of who is likely to benefit and who is unlikely to benefit
- A clear discussion of uncertainties, expected timelines and alternatives
- Pre-procedure steps, safety screening and an aftercare plan
- If any ovarian response is observed, the team may recommend a time-sensitive plan, such as planning an IVF cycle
Key points to know
- Ovarian rejuvenation is not guaranteed to improve egg quantity or quality
- Evidence is evolving, and success rates are not comparable to established IVF pathways
- It should be considered only after a comprehensive assessment and counselling